ANTIBACTERIAL ACTIVITY OF THE AG (I) COMPLEX WITH CYSTINE

Authors

  • V. Silnikov Institute of Chemical Biology and Fundamental Medicine SB RAS
  • Zh. Zhenwei Institute of Chemical Biology and Fundamental Medicine SB RAS
  • L. Chengjie Institute of Chemical Biology and Fundamental Medicine SB RAS

Keywords:

Silver complex, cystine, antibacterial activity, Pseudomonas aeruginosa, Staphylococcus аureus, Lactobacillus acidophilus

Abstract

This article is devoted to the primary study of the antibacterial activity of the silver-cystine complex against gram-negative and gram-positive pathogens, as well as the natural human microflora. High antibacterial activity against Pseudomonas aeruginosa and Staphylococcus aureus was shown, comparable to the activity of the antibiotic ciprofloxacin. Activity against Lactobacillus acidophilus is shown in a significantly higher concentration. The results obtained indicate the prospects of using this compound for the treatment of bacterial infections.

Author Biographies

V. Silnikov , Institute of Chemical Biology and Fundamental Medicine SB RAS

Doctor of Sciences

Zh. Zhenwei , Institute of Chemical Biology and Fundamental Medicine SB RAS

Linyi Institute of Industrial Technology

Linyi Applied Science and Technology Park

L. Chengjie , Institute of Chemical Biology and Fundamental Medicine SB RAS

Shandong Yang Du Jianhua Pharmaceutical Co., Ltd.

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Руководство по экспериментальному (доклиническому) изучению новых фармакологических веществ под общ. ред. Р.У.Хабриева, Москва, 2005.

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Published

2020-12-08

Issue

Vol. 2 No. 34(61) (2020)

Section

Статьи

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