FEATURES OF NEUROPLASTIC VARIABILITY OF PROJECTION NEURONS IN THE CONDITIONS OF EXPERIMENTAL DESTRUCTION OF VARIOUS STRUCTURES OF THE CENTRAL NERVOUS SYSTEM

Authors

  • S. Badalyan L.A. Orbeli Institute of Physiology, National Academy of Science Republic of Armenia, Yerevan

DOI:

https://doi.org/10.31618/nas.2413-5291.2021.2.66.407

Keywords:

neuroplastic variability of projection neurons;

Abstract

The morphological manifestations of neuroplastic variability of projection neurons were studied under conditions of experimental destruction of various structures of the central nervous system in animals. Various forms of pathological manifestations of neuroplastic variability of “survivors” (after exposure to a damaging factor) marked through the axonal transport system of neurons are shown. Marked nerve cells of an unusual, bizarre shape, denoted by the term "ugly neurons", are proposed to be considered as one of the criteria for the pathological manifestation of neuroplastic variability of projection neurons.

Author Biography

S. Badalyan , L.A. Orbeli Institute of Physiology, National Academy of Science Republic of Armenia, Yerevan

Dr. Biol of Science, Senior researcher

References

Badalyan S.A. ”Parnye kletki” kak morfologicheskij kriterij ocenki nejroplasticheskoj izmenchivosti v centralnoj nervnoj sisteme. V sb. “Aktualnye voprosy funkcionalnoj mezhpolusharnoj asimmetrii i nejroplastichnosti” (Materialy Vserossijskoj konf.-ciya s mezhdunarodnym uchastiem). M.: 2008. S.429-434.

Sotnikov O.S. Statika i strukturnaya kinetika zhivyh asinapticheskih dendritov. S-P.: «Nauka». 2008. 397s.

Badalyan S.A. Plastic reorganization in cerebellothalamic system after partial deafferentation of the ventrolateral nucleus of the thalamus. Neuroscience and Behavioral Physiology. 2005. V. 35. №1. P.43-47.

Badalyan S.A., Sargsyan V.A. Reorganization of the vestibulothalamic projections in lesions to the interpositus nucleus of the cerebellum and vestibular nucleus of Deiters. Neuroscience and Behavioral Physiology. 2008. V. 38. №8. P.767-773.

Berman A.L. The brain stem of the cat: A cytoarchitectonic altas with stereotaxic coordinates. Medison etc.: Univ. Wisc. Press. 1968. 176p.

Drachman D.A. Aging of the brain, entropy, and Alzheimer disease. Neurol. 2006. V.67. P.1340-1352.

Jasper H.H., Aimone-Marsan C.A. A stereotaxic atlas of the diencephalon of the cat. Ottawa: Nat. Res. Council Can. 1954. 90p.

Mesulam M.-M. Tetramethyl benzidine for HRP neurochemistry: a non-carcinogenic blue reaction-product with superior sensitivity for visualizing neural afferents and efferents. J. Histochem. and Cytochem. 1978. V. №2. P. 106-117.

Roy S., Zhang B., Lee V.M.-Y., Trojanowski J.Q. Axonal transport defects: a common theme in neurodegenerative diseases. Acta Neuropathologica. 2005. V.109. P.5 - 13.

Published

2021-05-14

Issue

Section

Статьи