RELATIONSHIP OF HEMOSTASIS AND FREE RADICAL OXIDATION IN PATIENTS WITH UTERINE CANCER

Authors

  • A. Gurina Federal State Budgetary Educational Institution of Higher Education Tyumen State Medical University of the Ministry of Health of the Russian Federation, Tyumen
  • E. Soldatova Regional Clinical Hospital No. 1, Tyumen

Keywords:

selmevitum, antioxidant potential, activation of hemostasis, coagulation.

Abstract

In the structure of mortality, oncological problems are of interest to one of the first places, that thrombosis appears as the second most frequent cause of death of cancer patients. Modern literature suggests the activation of the hemostatic system with the development of chronic DIC syndrome in cancer patients. Activation is realized primarily through an external mechanism of blood clotting: through tissue factor (TF) and so-called cancer procoagulants. The tissue factor, which is a complex of apoprotein III with phospholipid, appears as a trigger in this process, forming a complex with F. VII, which includes F. VII is activated, after which F is activated in accordance with the cascade folding scheme. X as part of the ff. TF / VII/Ha / Va and SA2 + complex.

Author Biography

E. Soldatova , Regional Clinical Hospital No. 1, Tyumen

Candidate of Medical Sciences, obstetrician-gynecologist

References

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Published

2021-05-14

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